Estrogens bind to receptors including GPER, which is generally located in cell membranes. The team of Didier Picard has however discovered a nuclear variant of GPER, which has different properties. This study, published on May 24, 2017 in Oncotarget, reveals that the fibroblasts carrying this variant facilitate the invasiveness of neighboring breast malignant cells.
Denis Duboule a été élu le 8 juin 2017 au Collège de France. Il y occupera la chaire “Évolution des Génomes et Développement”.
In collaboration with the Friedrich Miescher Institute, the team of David Shore has discovered the key role of a protein called Rif1 in the protection, stabilization and repair of damaged DNA. This study, published on June 17, 2017 in Nature Structural & Molecular Biology, uncovers a DNA maintenance function likely to be present in all eukaryotes.
Michael Hothorn has been selected by the Howard Hugues Medical Institute, the Bill & Melinda Gates Foundation, the Wellcome Trust, and the Calouste Gulbenkian Foundation as one of the International Research Scholars, early-career scientists poised to advance biology or medical research across the globe.
A study led by Ueli Schibler and Frédéric Gachon showed in mice that the size of the liver increases by almost half before returning to its initial dimensions, according to the phases of activity and rest, in a circadian fashion. Published on May 4, 2017 in Cell, this study describes the cellular mechanisms of this fluctuation, which disappears when the normal biological rhythm is reversed.
Florian Stern, doctorant des profs. Bruno Strasser (IUFE et Section de biologie) et Andreas Muller (IUFE), participera à la finale du concours ‘ma thèse en 180 secondes’, organisée le 18 mai 2017 à 18h30 à UniDufour, devant les caméras de la RTS !
Voir sa performance sur le déterminisme génétique et les intuitions humaines