In collaboration with researchers from Oslo University, Michael Hothorn’s team has analyzed the activation mechanism of two plant membrane receptor kinases, a steroid hormone receptor controlling plant growth, and a peptide hormone receptor controlling leave shedding. Both receptors rely on the same helper protein for activation. The helper uses two different areas to contact the respective receptor and to specifically read out the chemically diverse ligands. The researchers understand the underlying mechanisms in sufficient detail to lego-build functional receptor chimera that now allow to induce leave shedding by applying the plant steroid hormone normally triggering growth. These findings were published on March 12, 2018 in PNAS.
The group of Karl Perron reveals the strategies adopted by Pseudomonas aeruginosa, a bacterium that proliferates in the wounds of burn victims and threatens them with sepsis. Published on February 27, 2018 in Frontiers in Cellular and Infection Microbiology, this work opens the way to new therapies.
Denis Duboule donnera sa leçon inaugurale au Collège de France en tant que nouveau professeur et titulaire de la chaire internationale «Évolution des génomes et développement».
jeudi 8 février 2018, à 18h
Amphithéâtre Marguerite de Navarre
Collège de France
11, place Marcelin-Berthelot, Paris
La leçon inaugurale sera visible en direct sur le site du Collège de France.
The team of Juan Montoya has integrated a range of factors into a single statistical model to study the genesis of genetic diversity within a typical Amazonian species. This new approach, adaptable to any species, enables to assess the impact of present and future human large-scale alterations. The study was published on December 20, 2017 in PLoS ONE.
A study led by Sandra Citi shows that the proteins Zonula Occludens-1 and -2, which contribute to the tightness of the epithelium, perceive mechanical forces and activate different cellular responses accordingly. This novel process was unveiled on November 30, 2017 in the journal Current Biology.
This health tech company has been named on the MIT Technology Review 2017 list of ‘50 Smartest Companies’, which identifies companies creating new opportunities by combining important technologies and business savvy.
Our Section congratulates Jurgi Camblong, who has done his PhD and post-doc in the lab of Françoise Stutz.
BiOutils et TheScienceBreaker proposent aux enseignants un mini-magazine innovant pour une immersion au cœur de l’actualité scientifique. Composé d’articles vulgarisés et d’une activité pratique permettant de mieux comprendre la démarche scientifique sous-jacente, Break’d ! sera proposé tous les deux mois.
Des webinaires permettant aux élèves d’interagir directement avec un chercheur sont aussi prévus.