A study led by Denis Duboule and published in Science on November 21, 2014 reveals that the formation of these embryonic structures involves the action of a very similar group of genes and that they result from the implementation of a unique ancestral regulatory process.
The team of Emi Nagoshi shows that the fly and worm transcription factor p48 mammalian homologs share a role in protecting dopaminergic neurons from oxidative stress and degeneration. Their invertebrate genetic models of Parkinson’s disease are detailed in a study published on October 23, 2014 in PLoS Genetics.
Athanasia Tzika and Michel Milinkovitch participated to a study demonstrating that the emergence of mammals from egg-laying reptiles has been facilitated by the capture and recycling of a viral gene for the development of an evolutionary innovation: the placenta. The study was published on October 14, 2014 in PNAS.
In SIB, the group of Michel Milinkovitch forms the ‘Artificial & Natural Evolutionary Development of Complexity group’ for their activities in the physics of epithelia (including patterns of skin appendages and skin colour), comparative genomics/transcriptomics, and the development of stochastic heuristics for phylogeny inference.
Chaque année, Unitec, le bureau de transfert de technologies et de compétences de l’UNIGE et des HUG, accorde jusqu’à 5 bourses INNOGAP d’un montant maximum de 30’000 CHF chacune à des chercheurs de l’UNIGE et des HUG afin de soutenir financièrement des projets en phase de “preuve de concept” ou de prototypage.
Prochain délai de soumission de demandes : lundi 13 octobre 2014
David Shore’s group published in Genes & Development on August 1st, 2014 a detailed study of the promoter architecture of a large group of co-regulated genes, the ribosomal protein genes, which drive cell growth in yeast. In particular, this study reveals an unusual class of dynamic nucleosomes that may help to promote the high transcription level of these genes.
The article published in Science by Michel Milinkovitch’s team in 2013 is covered by Science in the Classroom, an education portal with a collection of annotated research papers and accompanying teaching materials for teachers and their students in high schools and universities.