Denis Duboule has been appointed as Chairman of the Board of Trustees of the Louis-Jeantet Foundation, as of January 2019.
The group of Paul Guichard has developed a technique to visualize cellular elements with a resolution unequalled in optical microscopy. Published on December 17, 2018 in Nature Methods, the results demonstrate how the researchers have succeeded in enlarging biological samples without deforming them and revealing details at a nanometric scale.
The team of Jan Pawlowski has developed an approach that combines genomics and machine learning tools to explore the microbial biodiversity of ecosystems. This new approach, published on December 13, 2018 in Trends in Microbiology, will enable the development of very efficient routine biomonitoring programs.
An ERC CoG has been awarded to Michael Hothorn for his research project entitled “System-wide discovery and analysis of inositol pyrophosphate signaling networks in plants (InsPire)”. The aim is to uncover nutrient signaling networks in plants.
The grant is endowed with 2 million Euros over 5 years.
The team of Sandra Citi has identified the mechanism that allows pores formed by the bacterial α-toxin to anchor to human epithelial cell membranes. The study, published on November 20, 2018 in Cell Reports, also demonstrates that blocking the assembly of the protein complex to which pores are docked allows cells to survive.
In collaboration with the University of Cambridge and the EPFL, the group of Denis Duboule has developed murine artificial pseudo-embryos capable of forming the three major axes of the body. These ‘gastruloids’, detailed on October 3, 2018 in Nature, possess a remarkable potential for the study of the early stages of normal or pathological embryonic development.
The team of Michel Milinkovitch has discovered that elephants regulate their body heat through their skin, which cracks into deep crevices, absorbing a maximum water. These results were published on October 2, 2018 in Nature Communications.
Video showing in detail the skin structure of the African elephant