A cellular sensor of phosphate levels

SPX domain with InsPAlong with researchers from UNIL, Michael Hothorn’s team reports that a region of specific proteins, the so-called SPX domain, signals the phosphate status to fungal, plant and human cells. This domain provides a binding surface for small molecules, the InsP, that regulate the uptake of phosphate into the cell. Their findings were published on April 14, 2016 in Science.

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