The role of the cellular entry point of anthrax is identified

Anthrax uses a receptor on the surface of cells to inject its lethal toxins. The team led by Marcos Gonzalez-Gaitan discovers the physiological function of this receptor, named Anthrax Toxin Receptor 2a (Antxr2a). These results, presented in Nature Cell Biology on December 2, 2012, reveal that Antxr2a actually plays a role in the embryonic development, orienting cell division along a specific plane, which is a prelude to the formation of future tissues and organs.

Press release