Watching the cogwheels of the biological clock in living cells

DBP, a protein whose expression fluctuates daily, regulates various genes involved in the inactivation of toxic substances ingested with food. The group of Ueli Schibler deciphered how the ‘clock genes’ control the rhythmic production of DBP in individual living cells. These molecular cogwheels were described in Molecular Cell on October 26, 2012.

Press release